IMPACT OF MUTATIONS IN THE HEMAGGLUTININ OF H10N7 VIRUSES ISOLATED FROM SEALS ON VIRUS REPLICATION IN AVIAN AND HUMAN CELLS

Impact of Mutations in the Hemagglutinin of H10N7 Viruses Isolated from Seals on Virus Replication in Avian and Human Cells

Wild birds are the reservoir for low-pathogenic avian influenza viruses, which are frequently transmitted to domestic birds and occasionally to mammals.In 2014, an H10N7 virus caused severe mortality in harbor seals Angled Hood in northeastern Europe.Although the hemagglutinin (HA) of this virus was closely related to H10 of avian H10N4 virus, it p

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Rapamycin administration causes a decrease in muscle contractile function and systemic glucose intolerance concomitant with reduced skeletal muscle Rictor, the mTORC2 component, expression independent of energy intake in young rats.

Emerging evidence suggests the potential of rapamycin, an antibiotic from Streptomyces hygroscopicus that functions as a mechanistic target of rapamycin (mTOR) inhibitor, as a mimetic of caloric restriction (CR) for maintaining skeletal muscle health.Several studies showed that rapamycin administration (RAP) reduced appetite and energy intake.Howev

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Mitigating psychological distress in healthcare workers as COVID-19 waves ensue: a repeated cross-sectional study from Jordan

Abstract Background Jordan has experienced several COVID-19 waves in the past 2 years.Cross-sectional studies have been conducted to evaluate distress in healthcare practitioners (HCPs), but there is limited evidence with regards to the impact of continuing pandemic waves on levels of distress in HCPs.We previously studied psychological distress in

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Reduction of Burnout Syndrome in Health Workers through a Cognitive-Behavioural Model-Based Program: A Pilot Study

Peruvian primary healthcare professionals experience high levels of burnout syndrome (BS).This study aims to assess the impact of a cognitive-behavioural model-based (CBMB) program as an occupational intervention to reduce burnout in primary healthcare providers.A total of 29 workers (intervention group = 16) took part in a CBMB intervention traini

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